Post by Nadica (She/Her) on Jul 19, 2024 1:13:05 GMT
COVID-19-Induced Bladder and Bowel Incontinence: A Hidden Morbidity? - Published April 17, 2023
Introduction
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported in the literature to cause persistent symptoms and long-term complications lasting for more than 1 month following acute infection known as long COVID or post-COVID syndrome. 1 However, knowledge of the long-term effects of the SARS-CoV-2 virus infection is still evolving. Better understanding of the varied long-term effects is essential to ensure that health care needs and expectations are met in patients with long COVID and support the development of dedicated medical and psychological services to look after patients experiencing long-term sequelae of the disease. 1
The cell-surface protein angiotensin-converting enzyme 2 (ACE2) has been identified as the main receptor for the SARS-CoV-2 spike protein. Its widespread distribution in various tissues accounts for the manifold manifestations of the disease in several organs. It has been shown to be highly expressed in the intestinal tract as well as the urothelium of the bladder.2-4
The purpose of this report is to present a small case series of 5 children presenting with new-onset bladder and bowel incontinence following COVID-19 infection and a review of the literature for reported potential pathophysiological mechanisms. To the best of our knowledge, this is the first report of this morbidity in children.
All cases are anonymized, and informed consent was obtained from each parent/patient prior to publication.
Introduction
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported in the literature to cause persistent symptoms and long-term complications lasting for more than 1 month following acute infection known as long COVID or post-COVID syndrome. 1 However, knowledge of the long-term effects of the SARS-CoV-2 virus infection is still evolving. Better understanding of the varied long-term effects is essential to ensure that health care needs and expectations are met in patients with long COVID and support the development of dedicated medical and psychological services to look after patients experiencing long-term sequelae of the disease. 1
The cell-surface protein angiotensin-converting enzyme 2 (ACE2) has been identified as the main receptor for the SARS-CoV-2 spike protein. Its widespread distribution in various tissues accounts for the manifold manifestations of the disease in several organs. It has been shown to be highly expressed in the intestinal tract as well as the urothelium of the bladder.2-4
The purpose of this report is to present a small case series of 5 children presenting with new-onset bladder and bowel incontinence following COVID-19 infection and a review of the literature for reported potential pathophysiological mechanisms. To the best of our knowledge, this is the first report of this morbidity in children.
All cases are anonymized, and informed consent was obtained from each parent/patient prior to publication.