RE: Paxlovid

userkn95101913 (you/pick)
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i avoided covid for 4 years with a mask and staying inside, then my mother gave it to me in 2024

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RE: Paxlovid Jul 4, 2024 2:10:41 GMT

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Post by userkn95101913 (you/pick) on Jul 4, 2024 2:10:41 GMT

Hi I'm new to this board, so I don't know 100% if this is the place I should be posting this question. Sorry if it's not.

I wanted to know if anyone here had solid research on the efficacy of Paxlovid against COVID, and exactly how well it prevents long-term effects such as long-COVID. I recently had COVID--definitely part of the summer surge of the FLiRT strain--and I treated it with Paxlovid. I already have multiple chronic conditions, and I want to know my chances of becoming more disabled might be. Thank you in advance.

Nadica (She/Her) Administrator I'm an Anomalocaris... I do my best! Posts: 2,785	RE: Paxlovid Jul 4, 2024 3:04:24 GMT Quote Select Post Deselect Post Link to Post Member Give Gift Back to Top Post by Nadica (She/Her) on Jul 4, 2024 3:04:24 GMT There's an expert on that kind of thing in the discord chat. I'll see if they can help with finding studies.
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Nadica (She/Her)
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RE: Paxlovid Jul 4, 2024 19:38:20 GMT

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Post by Nadica (She/Her) on Jul 4, 2024 19:38:20 GMT

Jul 4, 2024 2:10:41 GMT userkn95101913 (you/pick) said:

Hi I'm new to this board, so I don't know 100% if this is the place I should be posting this question. Sorry if it's not.

I wanted to know if anyone here had solid research on the efficacy of Paxlovid against COVID, and exactly how well it prevents long-term effects such as long-COVID. I recently had COVID--definitely part of the summer surge of the FLiRT strain--and I treated it with Paxlovid. I already have multiple chronic conditions, and I want to know my chances of becoming more disabled might be. Thank you in advance.

The expert in the chat directed me toward a couple sources of info and I was able to pick up a few from there. Maybe not precisely what you're looking for, but here's some studies on Nirmatrelvir (AKA Paxlovid) and its effects on post-covid sequelae as well as some general long covid and viral persistence studies:

Association of Treatment With Nirmatrelvir and the Risk of Post–COVID-19 Condition
The preprint of that if you're interested

A Veterans Administration news release about the study

Clinical Effectiveness of Ritonavir-Boosted Nirmatrelvir-A Literature Review

Analysis of All-Cause Hospitalization and Death Among Nonhospitalized Patients With Type 2 Diabetes and SARS-CoV-2 Infection Treated With Molnupiravir or Nirmatrelvir-Ritonavir During the Omicron Wave in Hong Kong

Nirmatrelvir and risk of hospital admission or death in adults with covid-19: emulation of a randomized target trial using electronic health records

The Potential Role of Viral Persistence in the Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) {More for a general understanding of what Paxlovid and other antiviral drugs could do to help prevent long covid, the mechanics}

Preprint: Effect of Paxlovid Treatment During Acute COVID-19 on Long COVID Onset: An EHR-Based Target Trial Emulation from the N3C and RECOVER Consortia

I was gonna post this one in the long covid science section today and figured It might be of some use data wise: Long COVID: major findings, mechanisms and recommendations

userkn95101913 (you/pick) Let me know if there's anything else I can help direct you towards.

Last Edit: Jul 4, 2024 19:39:02 GMT by Nadica (She/Her)

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Post by userkn95101913 (you/pick) on Jul 4, 2024 2:10:41 GMT

Post by Nadica (She/Her) on Jul 4, 2024 3:04:24 GMT

Post by Nadica (She/Her) on Jul 4, 2024 19:38:20 GMT

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