Post by Nadica (She/Her) on Sept 13, 2024 1:43:18 GMT
Main Predictors of Decreasing in Quality of Life in Patients With Post-COVID-19: A Cross-Sectional Study - Published Sept 9, 2024
Highlights
• Patients with post-COVID-19 alteration enhance the notion of a strong psychosomatic factors involved in the post-COVID-19 syndrome with a decrease in quality of life of millions of patients worldwide.
• The patients with post-COVID-19 alterations perceive a decreased quality of life probably due to effects of pain/discomfort, anxiety/depression (according to EQ-5D), and ≥3 persistent symptoms.
• The patients with post-COVID-19 alterations might benefit from neuropsychological rehabilitation programs even several months after disease onset.
Abstract
Objective
We aimed to assess physical and psychosomatic manifestations of patients with long COVID and their association with a decreased patient’s quality of life (QOL) or different times elapsed since the COVID-19 diagnosis.
Methods
This is a cross-sectional study. We retrospectively collected the clinical characteristics of adult patients who had tested positive for SARS-CoV-2 and had symptoms at least as early as 4 weeks after COVID-19 in México City between April 2020 and February 2021. A total of 179 were included. They answered questions to define chronic symptoms. The Sniffin’ Sticks Screening 12 test olfactory evaluation was performed. The diminish of QOL was defined by ≥10 points in the EuroQol visual analog scale between pre- and post-COVID-19, and each dimension of EQ-5D-5L test was evaluated. Chi-square test, Fisher’s exact test, Student t test, Wilcoxon rank-sum, and signed-rank test were used as required. A backward stepwise logistic regression analysis determined the factors associated with a decrease in QOL. All analyses were performed using R software version 3.6.3 (R Foundation).
Results
In the multivariable analysis, post-COVID-19 pain/discomfort (adjusted odds ratio [aOR] 2.5 [1.66-9.68]; P = .01), anxiety/depression (aOR 13 [1.44-17.23]; P = .03), and persistence of ≥3 symptoms (aOR 2.6 [0.96-7.47]; P = .05) remained statistically significant associated with decreased QOL.
Conclusions
Patients with long COVID-19 have decreased QOL mainly associated with pain/discomfort, anxiety/depression, and ≥3 persistent symptoms. Our findings enhanced the notion of a strong psychosomatic factors involved with long COVID-19. Therefore, these patients might benefit from neuropsychological rehabilitation, although the effect of such interventions should be evaluated.
Highlights
• Patients with post-COVID-19 alteration enhance the notion of a strong psychosomatic factors involved in the post-COVID-19 syndrome with a decrease in quality of life of millions of patients worldwide.
• The patients with post-COVID-19 alterations perceive a decreased quality of life probably due to effects of pain/discomfort, anxiety/depression (according to EQ-5D), and ≥3 persistent symptoms.
• The patients with post-COVID-19 alterations might benefit from neuropsychological rehabilitation programs even several months after disease onset.
Abstract
Objective
We aimed to assess physical and psychosomatic manifestations of patients with long COVID and their association with a decreased patient’s quality of life (QOL) or different times elapsed since the COVID-19 diagnosis.
Methods
This is a cross-sectional study. We retrospectively collected the clinical characteristics of adult patients who had tested positive for SARS-CoV-2 and had symptoms at least as early as 4 weeks after COVID-19 in México City between April 2020 and February 2021. A total of 179 were included. They answered questions to define chronic symptoms. The Sniffin’ Sticks Screening 12 test olfactory evaluation was performed. The diminish of QOL was defined by ≥10 points in the EuroQol visual analog scale between pre- and post-COVID-19, and each dimension of EQ-5D-5L test was evaluated. Chi-square test, Fisher’s exact test, Student t test, Wilcoxon rank-sum, and signed-rank test were used as required. A backward stepwise logistic regression analysis determined the factors associated with a decrease in QOL. All analyses were performed using R software version 3.6.3 (R Foundation).
Results
In the multivariable analysis, post-COVID-19 pain/discomfort (adjusted odds ratio [aOR] 2.5 [1.66-9.68]; P = .01), anxiety/depression (aOR 13 [1.44-17.23]; P = .03), and persistence of ≥3 symptoms (aOR 2.6 [0.96-7.47]; P = .05) remained statistically significant associated with decreased QOL.
Conclusions
Patients with long COVID-19 have decreased QOL mainly associated with pain/discomfort, anxiety/depression, and ≥3 persistent symptoms. Our findings enhanced the notion of a strong psychosomatic factors involved with long COVID-19. Therefore, these patients might benefit from neuropsychological rehabilitation, although the effect of such interventions should be evaluated.