Post by Nadica (She/Her) on Jul 31, 2024 0:26:13 GMT
New‐onset cutaneous kaposi’s sarcoma following SARS‐CoV‐2 infection - Published Nov 3, 2021
Abstract
Background
COVID‐19 is associated with several cutaneous manifestations, including chilbain‐like lesions, urticaria, erythema multiforme, and maculopapular lesions. Dermatoses may be directly linked to the viral infection or also represent a consequence of systemic therapies administrated for COVID‐19. A potential role of SARS‐CoV‐2 in triggering the reactivation of other viruses, such as HHV‐6, HHV‐7 and Epstein‐Barr virus has been hypothesized.
Objective
To better understand and hypothesize possible pathogenetic correlations of COVID‐19 with other dermatological conditions.
Methods
We report the case of an 83‐year‐old woman hospitalized in a nursing home for several years. On November 2020, the patient had been diagnosed with SARS‐CoV‐2 infection, with repeated positive swabs until January 2021. After a month, new‐onset asymptomatic cutaneous purplish macular lesions and violaceous patches occurred bilaterally on the feet.
Results
An incisional cutaneous biopsy and the histological examination of the plantar lesion revealed the diagnosis of Kaposi Sarcoma.
Conclusion
We report a unique case of new‐onset bilateral Kaposi's sarcoma following COVID‐19, speculating on a possible role of SARS‐CoV‐2 in the reactivation of human herpes virus‐8 (HHV‐8) infection.
Keywords: COVID‐19, kaposi sarcoma, SARS‐CoV‐2
Abstract
Background
COVID‐19 is associated with several cutaneous manifestations, including chilbain‐like lesions, urticaria, erythema multiforme, and maculopapular lesions. Dermatoses may be directly linked to the viral infection or also represent a consequence of systemic therapies administrated for COVID‐19. A potential role of SARS‐CoV‐2 in triggering the reactivation of other viruses, such as HHV‐6, HHV‐7 and Epstein‐Barr virus has been hypothesized.
Objective
To better understand and hypothesize possible pathogenetic correlations of COVID‐19 with other dermatological conditions.
Methods
We report the case of an 83‐year‐old woman hospitalized in a nursing home for several years. On November 2020, the patient had been diagnosed with SARS‐CoV‐2 infection, with repeated positive swabs until January 2021. After a month, new‐onset asymptomatic cutaneous purplish macular lesions and violaceous patches occurred bilaterally on the feet.
Results
An incisional cutaneous biopsy and the histological examination of the plantar lesion revealed the diagnosis of Kaposi Sarcoma.
Conclusion
We report a unique case of new‐onset bilateral Kaposi's sarcoma following COVID‐19, speculating on a possible role of SARS‐CoV‐2 in the reactivation of human herpes virus‐8 (HHV‐8) infection.
Keywords: COVID‐19, kaposi sarcoma, SARS‐CoV‐2